Description
COMPOSITION PER DOSE (1 mL)
Freeze-dried fraction:
• Live Canine Parvovirus (CPV) strain C-780916 ≥ 10⁶ TCID₅₀
• Live Canine Distemper Virus (CDV) Lederle strain ≥ 10⁴ TCID₅₀
• Live Canine Adenovirus type 2 (CAV2) Manhattan strain ≥ 10⁴ TCID₅₀
• Live Canine Parainfluenza Virus (CPIV) Penn strain 103/70 ≥ 10⁵ TCID₅₀
Liquid fraction:
• Inactivated Leptospira icterohaemorrhagiae ≥ 10⁹ microorganisms
• Inactivated Leptospira canicola ≥ 10⁹ microorganisms
Canine parvovirus infections, distemper, hepatitis, laryngotracheitis, tracheobronchitis, and leptospirosis are diseases that can affect dogs at any age and may even cause death. Puppies are protected in their first weeks of life by maternal antibodies, but as these decline, they become susceptible to infections again.
Systematic vaccination of puppies and adults ensures adequate antibody levels to protect against these diseases. In the case of asymptomatic carriers of leptospirosis, vaccination also helps reduce the risk of transmission to humans.
DOSAGE AND ADMINISTRATION
Dogs: Administer 1 ml per dog, regardless of weight, age, sex, or breed.
• Inject the liquid fraction into the vial containing the freeze-dried fraction and ensure complete reconstitution before use.
• First vaccination is recommended at 8 weeks of age, followed by revaccination at 12 weeks.
• Administer annual booster vaccinations thereafter.







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